Glucose sensor
Sensitivity:
The detection limit of these sensors for glucose is 3.5 µM. The sensitivity is approximately ... nA / µM at the physiological glucose concentrations in the extra cerebral fluid (~0.5mM).
Selectivity:
The sensor is independent of the variations in ascorbic acid and oxygen concentrations found in the brain. The sensor will not perform under anoxic conditions, but can be used under mild hypoxia.
Stability:
The sensors are very stable. Once implanted, stable measurements can be made for 4-6 weeks.
The sensors are made from Teflon coated Platinum-Iridium wire. The outer diameter is 175 µm which makes it suitable for in-brain implantation.
Application:
This glucose sensor is designed for implantation in the brain by stereotaxic surgery. It is based on the principles of constant potential amperometry, where a constant potential is delivered to the sensor by means of a potentiostat. This can be used for standard tethered recordings where the sensor is externally connected to a potentiostat (see image). This tethered application is useful for pharmacological profiling and other experiments were extended animal movement is not at issue.
| Type | Title | Size | Date |
 PDF | Glucose Sensor Information Flyer | 525 kbs | 10th May 2011 |
| PDF | Glucose Sensor User Guide | 680 kbs | 10th May 2011 |
